Can Vitamin D Reverse Prediabetes?

 In Prediabetes & Diabetes Prevention, Prediabetes Reversal, Research

What do vitamin D use and rates of prediabetes have in common?

Both have risen sharply in recent years.

Vitamin D use because of a number of factors.

Such as:

  • The suggested role of vitamin D in preventing various health problems
  • People are getting their vitamin D levels tested more than ever, and
  • A general wide spread deficiency in North Americans

Prediabetes rates have risen as a result of:

  • Increasing rates of obesity
  • Low physical activity rates
  • High consumption of highly refined carbs
  • As well as genetic factors we don’t yet fully understand

Although there is a lot of good evidence in the research showing prediabetes reversal is possible, and I see it in my own practice, we can always use more ways to prevent type 2 diabetes that are safe, effective and cheap.

And there may be a role for vitamin D to play.

There’s been some research that suggests that vitamin D could help reverse prediabetes, but up until this point, the research has not been conclusive.

And that’s where the D2d study comes in.

D2d is a large study being conducted in the United States.

The researchers have set out to answer the question:

Does supplementation of vitamin D delay the progression of prediabetes to type 2 diabetes? 

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The research participants are grouped into 1 or 2 groups:

  • Those that receive 4000IU of vitamin D daily or,
  • Those that receive a placebo (which is a “nothing pill”.)

The researchers will follow participants for a total of 2-4 years and test them for development of diabetes.

Up until now, research points to low vitamin D levels as a possible cause of increased risk of type 2 diabetes but there hasn’t been any conclusive evidence.

What’s the link?

There seems to be a relationship between both impaired pancreatic b-cell function and insulin resistance and low vitamin D levels.

Some small studies have shown insulin sensitivity increased with vitamin D supplementation.



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If D2d confirms the direct link between vitamin D and type 2 diabetes, then vitamin D supplementation will be likely standard practice in conventional medical approaches to prevent type 2 diabetes.

And use of vitamin D supplement could significantly help to reduce the rates of people progressing from prediabetes to type 2 diabetes.

Wouldn’t that be great?

The results of the study are expected in 2018. 

I’ll keep you posted 🙂

D2d is funded by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) of the National Institutes of Health (NIH),

For more information about the study and to sign up for updates go to their website here.


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